What is the function of the centromere in cell division?

The function of the centromere in cell division is primarily to hold sister chromatids together. During cell division, specifically in processes like mitosis and meiosis, chromosomes are duplicated and consist of two identical halves known as sister chromatids. The centromere is the region of the chromosome where these chromatids are tightly linked, creating a structural connection that is crucial for their movement and separation later in the process.

When a cell prepares to divide, it relies on the centromere to ensure that each daughter cell receives the correct number of chromosomes. During metaphase, spindle fibers attach to the centromeres via structures called kinetochores, which help to pull the sister chromatids apart during anaphase. This separation is essential for maintaining genetic stability, as each daughter cell requires a full set of chromosomes.

Therefore, the role of the centromere as a cohesive point is vital for the accurate division and allocation of genetic material during cell division.